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Flow Cytometry of T cells and T-cell Neoplasms

Jeffrey W Craig1, David M Dorfman1

  • 1Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Clinics in Laboratory Medicine
|November 13, 2017
PubMed

Keywords:
Flow cytometryImmunophenotypic analysisPan T-cell antigensT-cell neoplasia

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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