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Updated: Feb 18, 2026
Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
The relationship between ischaemia-modified albumin and good coronary collateral circulation
Murat Gök1, Harun Kundi, Emrullah Kızıltunç
1Cardiology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey. drmuratg@hotmail.com.
Background:
It is important to determine the grade of the coronary collateral circulation (CCC) in patients with stable coronary artery disease.
Aim:
In this study, we aimed to investigate the relationship between the ischaemia-modified albumin (IMA) level and good CCC.
Methods:
A total of 95 patients with coronary angiography and at least one epicardial coronary artery obstruction were included in the study. The Rentrop classification was used with CCC grading, where 0 and 1 were defined as poor collateral, and 2 and 3 were defined as good collateral. The IMA level of the patients was measured using an enzyme-linked immunosorbent assay (ELISA). The receiver-operating characteristic curve was used to show the sensitivity and specificity of IMA levels and the optimal cut-off value for predicting good CCC.
Results:
The multiple logistic regression analysis revealed that the IMA level in the good CCC group was higher (p < 0.045). Conversely, the high-sensitivity C-reactive protein level was lower in the good CCC group (p < 0.023). We found an IMA cut-off value (4.7 ng/mL) that indicated good CCC level, and this shows good CCC with 70.2% sensitivity and 60.3% specificity.
Conclusions:
The IMA level could serve as a simple and useful predictor of well-developed CCC.
