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Primary Subcutaneous Ewing Sarcoma Presented as Pseudo Aneurysmal Subcutaneous Tumor
Faten Hammedi1, Sonia Ziadi1, Mounir Trimeche1
1Department of Pathology, Farhat Hached Hospital, Sousse, Tunisia.
World Journal of Oncology
|November 18, 2017
Summary
Extraskeletal Ewing sarcoma, a rare malignant tumor, can occur in subcutaneous tissue, even in older adults. This case highlights its presentation as a shoulder mass, emphasizing the need for accurate diagnosis.
Area of Science:
- Oncology
- Dermatopathology
- Surgical Pathology
Background:
- Extraskeletal Ewing sarcoma (EES) is a rare mesenchymal malignancy.
- While typically found in deep soft tissues, EES in cutaneous or subcutaneous locations is exceptionally uncommon.
- This tumor, primarily affecting children, can rarely manifest in adults.
Observation:
- A case of subcutaneous Ewing sarcoma in a 49-year-old man's left shoulder is presented.
- Initial physical examination suggested a vascular tumor.
- Histopathological analysis revealed a small round cell tumor with strong CD99 expression.
Findings:
- The diagnosis of subcutaneous Ewing sarcoma was confirmed.
- The tumor showed no osseous involvement.
- Immunohistochemistry was crucial for diagnosis, with strong CD99 positivity.
Implications:
- Ewing sarcoma is a rare malignant small round cell tumor of the skin and subcutaneous tissue.
- Accurate differentiation from other small round cell cutaneous neoplasms is essential.
- This case expands the understanding of EES presentation in adults and superficial locations.

