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Primary Hepatic Neuroendocrine Tumor: What Do We Know Now?
1National Capital Consortium, National Naval Medical Center, Department of Surgery, 8901 Wisconsin Ave, Bethesda, MD 20889, USA.
World Journal of Oncology
|November 18, 2017
Summary
Primary hepatic neuroendocrine tumors (PHNETs) are rare. Diagnosis involves exclusion and histology, with surgery offering good prognosis but requiring long-term follow-up due to recurrence risk.
Area of Science:
- Hepatology
- Oncology
- Pathology
Background:
- Primary hepatic neuroendocrine tumors (PHNETs) are exceptionally rare neoplasms.
- Limited knowledge exists due to the low incidence of these tumors.
- Accurate diagnosis requires a systematic approach involving clinical exclusion and histological confirmation.
Purpose of the Study:
- To elaborate on the key features of PHNETs.
- To outline a diagnostic algorithm for PHNETs.
- To review current management strategies, alternative treatments, and existing literature on PHNETs.
Main Methods:
- Systematic clinical exclusion.
- Histological confirmation.
- Comprehensive literature review.
Main Results:
- PHNETs necessitate a rigorous diagnostic process.
- Surgical treatment is associated with an excellent prognosis.
- A high rate of tumor recurrence mandates long-term patient follow-up.
Conclusions:
- Early and accurate diagnosis of PHNETs is crucial.
- Surgical resection is the primary treatment modality for PHNETs.
- Ongoing surveillance is essential for managing the risk of recurrence in PHNET patients.
