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Hypertrophic Pulmonary Osteoarthropathy: A Case Report.
Eric Royston1, Khalil Katato2, Dan Mesko1
1Genesys Regional Medical Center,One Genesys Parkway,Grand Blanc, MI 48439, USA.
World Journal of Oncology
|November 18, 2017
Summary
A patient with lung cancer experienced leg pain due to hypertrophic pulmonary osteoarthropathy. This condition, often linked to lung malignancies, can cause significant discomfort.
Area of Science:
- Oncology
- Pulmonology
- Rheumatology
Background:
- Sarcomatoid carcinoma of the lung is a rare and aggressive subtype of non-small cell lung cancer.
- Hypertrophic pulmonary osteoarthropathy (HPO) is a paraneoplastic syndrome characterized by digital clubbing, arthritis, and subperiosteal new bone formation.
Observation:
- A 42-year-old male presented with dyspnea and severe bilateral lower extremity pain.
- Diagnostic workup confirmed sarcomatoid carcinoma of the lung.
Findings:
- Bone scintigraphy revealed findings consistent with hypertrophic pulmonary osteoarthropathy.
- HPO was identified as the cause of the patient's debilitating lower extremity pain.
Implications:
- This case highlights the importance of considering HPO in lung cancer patients presenting with bone pain.
- Early diagnosis and management of HPO can improve patient quality of life.
- Further research into the mechanisms of HPO in lung cancer is warranted.
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