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Loose anagen syndrome
1Department of Dermatology, Kaiser Permanente Medical Center, San Francisco, California.
Journal of the American Academy of Dermatology
|February 1, 1989
Summary
Loose anagen syndrome is a hair condition where hairs are loosely anchored and easily pulled. This affects children and adults, causing sparse hair that doesn't grow long.
Area of Science:
- Dermatology
- Trichology
- Pediatric Hair Disorders
Background:
- Loose anagen syndrome (LAS) is a hair condition characterized by loosely anchored anagen hairs.
- It primarily affects children, leading to sparse hair that is easily epilated.
Observation:
- Patients present with sparse hair that does not attain significant length.
- Easily epilated hairs are misshapen anagen hairs lacking external root sheaths.
- Histological examination reveals abnormal premature keratinization in the inner root sheath.
Findings:
- The study describes findings in 22 children and five adults with LAS.
- While hair length and density improve with age, the loose anchoring persists into adulthood.
- The condition affects both sexes and can occur in individuals with various hair colors, though blond girls aged 2-5 years are most commonly observed.
Implications:
- Understanding the pathophysiology of LAS aids in diagnosis and management.
- Further research into the specific mechanisms of abnormal keratinization is warranted.
- This condition highlights the complex factors influencing hair anchorage and growth cycles.