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Updated: Feb 18, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
New Concepts Related to Disease Appreciation in Multiple Sclerosis
Christina J Azevedo1, Amirhossein Jaberzadeh1, Daniel Pelletier1
1Department of Neurology, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, Suite 206, Los Angeles, CA 90033, USA.
Abstract:
In the past several decades, MRI has become an indispensable tool in the field of multiple sclerosis (MS) for clinicians and researchers. However, the MS field still faces several challenges. This review focuses on 2 current areas of difficulty: 1) discriminating MS from other diseases when the clinical history and imaging features are atypical or nonspecific, and 2) the lack of quantitative imaging metrics with which to follow MS patients over time in clinical practice. This review highlights promising MRI and postprocessing techniques that have potential applications in these areas. With further study, these tools could be usefully integrated into clinical care.
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