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Hypodermis01:02

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The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
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In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
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The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
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The human X chromosome contains over ten times the number of genes as in the Y chromosome. Since males have only one X chromosome, and females have two, one might expect females to produce twice as many of the proteins, with undesirable results.
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Ichthyosis Hystrix.

K N Saxsena, M M Singh, K K Sharma

    Indian Journal of Dermatology and Venereology
    |November 22, 2017
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    Summary
    This summary is machine-generated.

    This study reports three rare cases of ichthyosis hystrix within a single family. This genetic skin condition

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    Area of Science:

    • Dermatology
    • Medical Genetics

    Background:

    • Ichthyosis hystrix is a rare genetic disorder characterized by excessive skin scaling.
    • Familial inheritance patterns are crucial for understanding rare dermatological conditions.

    Observation:

    • Three distinct cases of ichthyosis hystrix were identified within the same family.
    • This represents a highly unusual occurrence for this specific ichthyosis subtype.

    Findings:

    • The co-occurrence of three ichthyosis hystrix cases in one family suggests a potential genetic predisposition or a specific inheritance pattern.
    • Detailed genetic analysis is warranted to elucidate the underlying mechanisms.

    Implications:

    • Understanding familial ichthyosis hystrix can aid in genetic counseling and family planning.
    • Further research into this rare condition may reveal novel insights into keratin disorders.