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Updated: Aug 10, 2026

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Neurohormonal aspects of fibromyalgia syndrome
1Department of Medicine, University of Texas Health Science Center, San Antonio.
Abstract:
There is a growing awareness that fibrositis/fibromyalgia syndrome is a systemic disorder for which a pathogenic mechanism must be sought. A generalized deficiency of the neurotransmitter, serotonin could explain many of fibromyalgia's typical manifestations. The serotonin deficiency hypothesis is appealing because it provides a number of experimental approaches that can now be used to further study the pathogenesis of this disorder.
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