Related Experiment Video
Updated: Jul 26, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
COMPARISON OF RESPONSE OF PASSIVE DOSIMETRY SYSTEMS IN SCANNING PROTON RADIOTHERAPY-A STUDY USING PAEDIATRIC
Ž Kneževic1, I Ambrozova2, C Domingo3
1Ruder Boškovic Institute, Bijenicka cesta 54, Zagreb, Croatia.
This study evaluated dosimetry systems for proton beam therapy in child phantoms. Radiophotoluminescent detectors showed less sensitivity to neutrons, aiding gamma dose assessment in pediatric cancer treatment.
Area of Science:
- Medical Physics
- Radiation Oncology
- Dosimetry
Background:
- Proton beam therapy offers advantages over photon radiotherapy, including precise dose delivery and sparing of healthy tissues.
- This is particularly crucial for pediatric cancer patients and tumors near critical organs.
- Proton interactions generate secondary radiation (neutrons, gamma rays), necessitating accurate dosimetry in mixed fields.
Purpose of the Study:
- To compare the performance of various passive dosimetry systems in a mixed radiation field.
- To assess dose measurements in anthropomorphic phantoms simulating pediatric patients (5 and 10 years old).
- To evaluate dosimetry for proton pencil beam scanning techniques in a pediatric context.
Main Methods:
- Irradiation of anthropomorphic phantoms using a proton pencil beam.
- Dose measurements in various organs using thermoluminescent dosimeters (MTS-7, MTS-6, MCP-N), radiophotoluminescent dosimeters (GD-352 M, GD-302M), bubble detectors, and PADC track detectors.
- Comparison of detector responses in the mixed neutron and gamma radiation field.
Main Results:
- Radiophotoluminescent (RPL) detectors demonstrated lower sensitivity to neutrons compared to LiF thermoluminescent dosimeters (TLDs).
- RPL detectors are suitable for measuring the gamma component of the dose within phantoms.
- Neutron doses measured by track detectors, bubble detectors, and MTS-7/MTS-6 pairs were consistent within uncertainty.
Conclusions:
- The study provides crucial data on dosimetry system performance in pediatric proton therapy scenarios.
- RPL detectors offer a viable option for assessing gamma radiation contributions in mixed fields.
- This research is the first to conduct such measurements on child anthropomorphic phantoms using pencil scanning proton beams.
More Related Videos
09:49A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
07:57Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
Published on: March 24, 2022
Related Concept Videos
Biological Effects of Radiation
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET