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Measuring evolutionary rates of proteins in a structural context.

Dariya K Sydykova1, Benjamin R Jack1, Stephanie J Spielman2

  • 1Department of Integrative Biology, The University of Texas at Austin, Austin, TX, 78712, USA.

F1000Research
|November 24, 2017
PubMed
Summary

This study introduces methods to measure protein evolution rates at specific sites and link them to protein structure. We offer two calculation approaches and provide code to aid researchers in evolutionary and structural biology analyses.

Keywords:
Protein evolutionevolutionary ratemultiple sequence alignmentprotein structurerelative solvent accessibilityweighted contact number

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