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A new steroidal saponin from Polygonatum sibiricum
Hong-Yang Zhang1,2, Wei-Cheng Hu3,4, Guo-Xu Ma2
1a Center of Research and Development on Life Sciences and Environment Sciences , Harbin University of Commerce , Harbin 150076 , China.
Abstract:
A new furostan type steroidal saponin, kingianoside Z (1), along with four known compounds (2-5), was isolated from the ethanolic extract of Polygonatum sibiricum Delar. ex Redoute. Their structures were determined by spectroscopical method and by comparison with previously reported spectroscopic data. Compounds 3-5 showed significant cytotoxicity against HepG2 cell lines with IC50 values of 14.2, 12.1 and 8.5 μM, respectively.

