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Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids01:21

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

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Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
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Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents01:29

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

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Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
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Herbs and Inflammatory Bowel Disease.

Gregory M Sebepos-Rogers1, David S Rampton2

  • 1Department of Gastroenterology, Royal London Hospital, Barts Health NHS Trust, Whitechapel Road, London E1 1BB, UK.

Gastroenterology Clinics of North America
|November 28, 2017
PubMed
Summary

Herbal remedies for inflammatory bowel disease (IBD) lack strong evidence and may pose risks. More research is needed to confirm their benefits and safety for IBD patients.

Keywords:
Crohn diseaseHerbal medicinesHerbsInflammatory bowel diseaseUlcerative colitis

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Area of Science:

  • Gastroenterology
  • Pharmacology
  • Integrative Medicine

Background:

  • Herbal preparations are frequently used by patients diagnosed with inflammatory bowel disease (IBD).
  • Current evidence supporting the efficacy of these herbal treatments in IBD management is limited.
  • Potential safety concerns associated with herbal product use in IBD patients exist.

Purpose of the Study:

  • To review the existing evidence on the efficacy and safety of herbal preparations for inflammatory bowel disease (IBD).
  • To highlight the need for larger, high-quality clinical trials to validate the therapeutic potential of herbal remedies in IBD.
  • To emphasize the importance of patient and healthcare provider education regarding the risks and limitations of using herbal products for IBD.

Main Methods:

  • Systematic review of existing literature on herbal preparations and IBD.
  • Analysis of small-scale studies and clinical trials assessing herbal efficacy.
  • Evaluation of reported safety data and potential adverse effects.

Main Results:

  • Limited and variable quality evidence suggests potential benefits of some herbal preparations in IBD.
  • Larger, well-designed trials are necessary to confirm efficacy in inducing and maintaining remission.
  • Significant gaps in knowledge regarding the safety profile of many herbal products for IBD patients.

Conclusions:

  • The efficacy of herbal preparations for inflammatory bowel disease (IBD) is not well-established.
  • Further rigorous research is required to determine the role of herbal remedies in IBD treatment.
  • Increased awareness among patients and healthcare professionals about the risks and limitations of herbal products is crucial.