Molecular mimicry modulates plant host responses to pathogens
1Department of Plant Pathology and the Genome Center, University of California, Davis, CA, USA.
Annals of Botany
|November 29, 2017
Summary
Plant pathogens use molecules that mimic plant hormones to evade immunity. The bacterial protein RaxX mimics a plant peptide hormone, impacting the rice immune receptor XA21.
Area of Science:
- Plant Pathology
- Molecular Plant-Microbe Interactions
- Plant Immunity
Background:
- Pathogens secrete molecules that mimic host compounds.
- Some microbial molecules mimic plant hormones crucial for development and immunity.
Purpose of the Study:
- To review microbial molecules that mimic host molecules.
- To highlight the RaxX protein from Xanthomonas oryzae pv. oryzae as a case study.
- To explore the RaxX/XA21 interaction in rice.
Main Methods:
- Literature review of microbial mimicry in plant pathogens.
- Focus on bacterial, fungal, and nematode examples.
- Detailed analysis of the RaxX protein and its interaction with the XA21 immune receptor.
Main Results:
- RaxX, a bacterial protein, mimics the plant peptide hormone PSY (plant peptide containing sulphated tyrosine).
- The rice immune receptor XA21 detects RaxX but not endogenous PSY.
- The RaxX/XA21 system provides insights into host-pathogen interactions.
Conclusions:
- Microbial mimicry is a significant strategy employed by plant pathogens.
- The RaxX/XA21 system offers a model for understanding differential receptor activation.
- Future research can leverage this system to explore host immunity and pathogen evasion.
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