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Updated: Feb 17, 2026

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Published on: October 20, 2011
Orofacial Bacterial Infectious Diseases: An Update
1Department of Oral Pathology, Dental Research Center, Research Centre for Molecular Medicine, Dental Faculty, Hamadan University of Medical Sciences, Hamadan, Iran.
Oral infections, often from odontogenic sources, can impact systemic health and involve skin tissues. Prompt diagnosis and recognition of clinical signs are vital for effective orofacial health management.
Area of Science:
- Oral Medicine
- Infectious Diseases
- Dermatology
Background:
- Odontogenic infections are common, treatable via dental or surgical interventions.
- Systemic diseases like tuberculosis and syphilis can manifest as oral infectious lesions.
- Infectious diseases can affect skin and underlying tissues, ranging from superficial to necrotizing fasciitis.
Purpose of the Study:
- To review the literature on oral infections and their systemic implications.
- To highlight the connection between oral health, skin infections, and overall patient well-being.
- To emphasize the importance of accurate diagnosis in managing orofacial infections.
Main Methods:
- Extensive literature search conducted in PubMed, Google Scholar, and Scopus databases.
- Articles published between 1980 and 2017 were included in the analysis.
- Systematic review and analysis of relevant research articles.
Main Results:
- The majority of oral infections stem from odontogenic origins.
- Skin and subcutaneous tissue infections, including necrotizing fasciitis, are associated with infectious diseases.
- A significant link exists between oral infections and potential systemic involvement.
Conclusions:
- The interplay between the oral cavity, facial skin, and other organs poses life-threatening risks.
- Accurate diagnosis and recognition of clinical findings are critical for improving orofacial health.
- Effective management requires a comprehensive understanding of infectious disease pathways.
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