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Related Experiment Video

Updated: Feb 17, 2026

Transretinal ERG Recordings from Mouse Retina: Rod and Cone Photoresponses

Transretinal ERG Recordings from Mouse Retina: Rod and Cone Photoresponses

Published on: March 14, 2012

High-Throughput Binocular Pattern Electroretinograms in the Mouse.

Tsung-Han Chou¹, Jonathon Toft-Nielsen², Vittorio Porciatti³

¹Bascom Palmer Eye Institute, McKnight Vision Research Center, University of Miami Miller School of Medicine, 1638 NW 10th Avenue, Room 507A, Miami, FL, 33136, USA.

Methods in Molecular Biology (Clifton, N.J.)

|December 1, 2017

Summary

This summary is machine-generated.

Researchers developed a novel method for simultaneous, user-friendly pattern electroretinograms (PERG) from both eyes. This technique utilizes asynchronous binocular stimulation and single-channel signal acquisition for robust results.

Keywords:

Mouse PERG Pattern electroretinogram Retinal ganglion cell

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Related Experiment Videos

Last Updated: Feb 17, 2026

Transretinal ERG Recordings from Mouse Retina: Rod and Cone Photoresponses

Transretinal ERG Recordings from Mouse Retina: Rod and Cone Photoresponses

Published on: March 14, 2012

Direct-Coupled Electroretinogram DC-ERG for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium

Direct-Coupled Electroretinogram DC-ERG for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium

Published on: July 14, 2020

Simultaneous ex vivo Functional Testing of Two Retinas by in vivo Electroretinogram System

Simultaneous ex vivo Functional Testing of Two Retinas by in vivo Electroretinogram System

Published on: May 6, 2015

Area of Science:

Ophthalmology
Neuroscience
Biomedical Engineering

Background:

Pattern electroretinograms (PERG) are crucial for assessing retinal function.
Simultaneous binocular PERG recording is challenging due to signal crosstalk and acquisition complexity.

Purpose of the Study:

To introduce a novel, simplified method for obtaining simultaneous bilateral PERG.
To enhance the user-friendliness and robustness of PERG measurements.

Main Methods:

Asynchronous binocular stimulation was employed to differentiate signals from each eye.
A single-channel acquisition system was utilized.
Subcutaneous needle electrodes were placed in the snout for signal recording.

Main Results:

The new method successfully acquired user-friendly and robust PERG signals simultaneously from both eyes.
The technique demonstrated effectiveness in capturing binocular visual responses.

Conclusions:

This innovative approach simplifies simultaneous binocular PERG acquisition.
The described method offers a robust and user-friendly alternative for retinal function assessment.