Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Targeted Inhibition of MEGF10-Mediated Astrogliosis Reduces Glial Scar Formation and Promotes Neurofunction Recovery in Mice After Stroke.

Glia·2026

Same author

Interferon-γ-Responsive Microglia-Derived Extracellular Vesicles Inhibited Neurogenesis After Stroke via MicroRNA-199a-5p/<i>SIRT1</i> Axis.

Journal of the American Heart Association·2026

Same author

Immediate and long-term effects of orbitofrontal cortex stimulation on EEG microstates in schizophrenia.

Translational psychiatry·2026

Same author

Dual-Functionalized Extracellular Vesicles Promote Brain Repair and Remodeling Following Ischemic Stroke in Mice.

CNS neuroscience & therapeutics·2025

Same author

State-dependent neurovascular modulation induced by transcranial ultrasound stimulation.

Medical & biological engineering & computing·2025

Same author

Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice.

Neural regeneration research·2024

Same journal

Evaluating a Novel Cell-Free Preservation Solution for Human Cardiomyocyte Protection: A Proof-of-Concept Study.

BioMed research international·2026

Same journal

Clinical Efficacy of Chinese Medicine in Treating Adult Henoch-Schönlein Purpura: A Meta-Analysis.

BioMed research international·2026

Same journal

RETRACTION: Rehabilitation Training and Resveratrol Improve the Recovery of Neurological and Motor Function in Rats after Cerebral Ischemic Injury through the Sirt1 Signaling Pathway.

BioMed research international·2026

Same journal

The Oncogenic and Tumor-Suppressive Roles of SNHG18: A Double-Edged Long Noncoding RNA in Cancer.

BioMed research international·2026

Same journal

Evaluation of LncRNA NEAT1 and MEG3 Expression Levels in Hospitalized COVID-19 Patients.

BioMed research international·2026

Same journal

Perceived Self-Efficacy and Its Determinants for Noncommunicable Disease Prevention Among Adults in Southern Ethiopia: A Community-Based Cross-Sectional Study.

BioMed research international·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 17, 2026

Functional MRI in Conjunction with a Novel MRI-compatible Hand-induced Robotic Device to Evaluate Rehabilitation of Individuals Recovering from Hand Grip Deficits

Functional MRI in Conjunction with a Novel MRI-compatible Hand-induced Robotic Device to Evaluate Rehabilitation of Individuals Recovering from Hand Grip Deficits

Published on: November 23, 2019

Functional Activation-Informed Structural Changes during Stroke Recovery: A Longitudinal MRI Study.

Zhiyuan Wu¹, Lin Cheng², Guo-Yuan Yang²

¹Department of Interventional Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Biomed Research International

|December 6, 2017

Summary

This summary is machine-generated.

Stroke recovery involves brain changes. This study combined functional and structural MRI data to reveal how brain structure adapts, offering new insights into stroke recovery mechanisms and plasticity.

More Related Videos

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Published on: September 1, 2023

Use of a Foot-Induced Digitally Controlled Resistance Device for Functional Magnetic Resonance Imaging Evaluation in Patients with Foot Paresis

Use of a Foot-Induced Digitally Controlled Resistance Device for Functional Magnetic Resonance Imaging Evaluation in Patients with Foot Paresis

Published on: July 7, 2023

Related Experiment Videos

Last Updated: Feb 17, 2026

Functional MRI in Conjunction with a Novel MRI-compatible Hand-induced Robotic Device to Evaluate Rehabilitation of Individuals Recovering from Hand Grip Deficits

Functional MRI in Conjunction with a Novel MRI-compatible Hand-induced Robotic Device to Evaluate Rehabilitation of Individuals Recovering from Hand Grip Deficits

Published on: November 23, 2019

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Published on: September 1, 2023

Use of a Foot-Induced Digitally Controlled Resistance Device for Functional Magnetic Resonance Imaging Evaluation in Patients with Foot Paresis

Use of a Foot-Induced Digitally Controlled Resistance Device for Functional Magnetic Resonance Imaging Evaluation in Patients with Foot Paresis

Published on: July 7, 2023

Area of Science:

Neuroimaging
Stroke Recovery Research
Neuroplasticity

Background:

Stroke recovery involves functional reorganization and structural brain changes.
Previous studies often analyzed functional and structural data separately, potentially missing integrated insights.
Lesion heterogeneity can complicate the interpretation of stroke recovery findings.

Purpose of the Study:

To investigate functional activation-informed structural brain changes during stroke recovery.
To explore the relationship between structural changes in activated motor regions and motor function.
To propose an integrated approach for studying post-stroke plasticity.

Main Methods:

Utilized MRI data from twelve stroke patients over three months post-stroke.
Employed functional activation during a finger-tapping task to guide structural analysis.
Correlated structural changes in motor-related activated regions with motor function recovery (Fugl-Meyer Index).

Main Results:

Increased averaged gray matter volume (aGMV) and gray matter volume laterality index (LI_GMV) in contralesional activated regions during recovery.
Positive correlation between LI_GMV and Fugl-Meyer Index (FMI) early in recovery.
Negative correlation between aGMV of bilateral activated regions and FMI throughout recovery.

Conclusions:

Combining functional and structural neuroimaging provides deeper understanding of stroke recovery.
The study highlights innate plasticity processes following stroke.
A novel approach integrating functional and structural data for stroke research is proposed.