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Ultrastretchable Kirigami Bioprobes.
Yusuke Morikawa1, Shota Yamagiwa1, Hirohito Sawahata1
1Department of Electrical and Electronic Information Engineering, Toyohashi University of Technology, 1-1 Hibarigaoka Tempaku-cho, Toyohashi, 441-8580, Japan.
Advanced Healthcare Materials
|December 9, 2017
Summary
Researchers developed an ultrastretchable electronic film using a Kirigami design. This flexible device can conform to biological tissues and record vital signals from the brain and heart.
Area of Science:
- Materials Science
- Bioelectronics
- Biomedical Engineering
Background:
- Developing flexible electronics for interfacing with soft biological tissues is challenging.
- Existing devices often lack the necessary stretchability and conformability for dynamic organs.
Purpose of the Study:
- To create an ultrastretchable film device capable of conforming to large, deformable biological samples.
- To demonstrate the utility of this device for in vivo electrophysiological recordings.
Main Methods:
- Fabrication of a parylene film with platinum/titanium microelectrodes patterned with Kirigami slits.
- Characterization of the film's mechanical properties, including stretchability and Young's modulus.
- In vivo electrophysiological recordings from mouse brain and heart tissues.
Main Results:
- The Kirigami-designed film achieved high stretchability (up to ≈840%) with a low Young's modulus (as low as 3.6 kPa).
- The device successfully recorded in vivo electrocorticogram signals from mouse cortices.
- In vivo epicardial electrocardiogram signals were recorded from a beating mouse heart.
Conclusions:
- The Kirigami-based ultrastretchable film device offers a promising platform for advanced bioelectronic interfaces.
- Its conformability and recording capabilities minimize stress on soft tissues, enabling new possibilities in physiological monitoring.
