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[Recurrent postpartum pyoderma gangrenosum and fatal cardiomyopathy]
I Naciri1, M Meziane1, L Benzekri1
1Service de dermatologie et vénérologie, faculté de médecine et de pharmacie, université Mohammed V, centre hospitalier universitaire Ibn Sina, BP 6527, 10100 Rabat, Maroc.
Annales De Dermatologie Et De Venereologie
|December 11, 2017
Summary
Recurrent pyoderma gangrenosum (PG) during pregnancy is rare. This case highlights a fatal association between postpartum pyoderma gangrenosum and postpartum cardiomyopathy (PPCM).
Area of Science:
- Obstetrics and Gynecology
- Dermatology
- Cardiology
Background:
- Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis.
- Pregnancy can be a trigger for recurrent PG.
- Postpartum cardiomyopathy (PPCM) is a severe form of heart failure.
Observation:
- A 23-year-old woman experienced recurrent PG during her fifth pregnancy, presenting as a painful ulceration near a Cesarean scar.
- Despite antibiotic treatment, the ulcer worsened, and histological examination confirmed PG.
- Corticosteroid therapy for PG preceded the sudden onset of heart failure symptoms.
Findings:
- Trans-thoracic echocardiography confirmed PPCM in the patient.
- The patient's outcome was fatal, underscoring the severity of the combined conditions.
- The case suggests a potential link between PG and PPCM in the postpartum period.
Implications:
- This case raises questions about the relationship between PG and pregnancy.
- The association of PG and PPCM may be linked to pregnancy-induced hormonal changes and inflammatory processes.
- Further research is needed to understand the pathogenesis and management of PG during pregnancy and its potential cardiac complications.
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