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The Impact of Dose Reduction in Quantitative Kinematic CT of Ankle Joints Using a Full Model-Based Iterative
Charles Lombard1, Alban Gervaise2, Nicolas Villani3
11 Service d'Imagerie Guilloz, Centre Hospitalier Régional Universitaire de Nancy, 29 Avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy Cedex, France.
AJR. American Journal of Roentgenology
|December 13, 2017
Summary
Low-dose kinematic CT scans using full model-based iterative reconstruction (MBIR) enable reliable ankle measurements. However, ultra-low-dose protocols compromise accuracy and reproducibility, indicating caution is needed for diagnostic imaging.
Area of Science:
- Radiology
- Medical Imaging
- Orthopedics
Background:
- Kinematic CT is crucial for ankle joint assessment.
- Semiautomatic measurements offer efficiency but require validation.
- Iterative reconstruction techniques like MBIR can improve image quality at lower doses.
Purpose of the Study:
- To assess the quality and reproducibility of semiautomatic ankle measurements using low-dose kinematic CT with full model-based iterative reconstruction (MBIR).
- To determine the impact of varying radiation doses on measurement accuracy and reliability.
Main Methods:
- Cadaveric ankle CT scans were acquired at standard, low (10% of standard), and ultra-low (1.5% of standard) dose levels.
- Images were reconstructed using a full MBIR algorithm.
- Two semiautomatic measurements (distance and angle) were performed by two readers, evaluating registration error and reproducibility (Intraclass Correlation Coefficient - ICC).
Main Results:
- Standard and low-dose protocols demonstrated good registration quality (0.65-4.72% error), similar measurements (p=0.9), and excellent reproducibility (ICC=0.881).
- Ultra-low-dose protocol resulted in poor registration quality, significantly different measurements (p<0.001), and poor reproducibility (ICC=0.39).
- In a specimen without metallic implants, measurements were reliable across all dose levels.
Conclusions:
- Full MBIR facilitates reliable and reproducible ankle kinematic CT measurements with a low-dose protocol.
- Ultra-low-dose protocols should be used cautiously as they may yield unreliable results.
- MBIR demonstrates potential for dose reduction in kinematic CT while maintaining diagnostic quality.
