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BEAMing LAMP: single-molecule capture and on-bead isothermal amplification for digital detection of hepatitis C virus
Jiyun Chen1, Xiaomin Xu, Zhimei Huang
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China. jianhuijiang@hnu.edu.cn tanglijuang@hnu.edu.cn.
Chemical Communications (Cambridge, England)
|December 14, 2017
Abstract:
A novel dNAD platform (BEAMing LAMP) by combining emulsion micro-reactors, single-molecule magnetic capture and on-bead loop-mediated isothermal amplification has been developed for DNA detection, which enables absolute and high-precision quantification of a target with a detection limit of 300 copies.
