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Updated: Feb 16, 2026

Multiple Intravenous Bolus Dosing and Invasive Hemodynamic Assessment in a Hypoxia-Induced Mouse Pulmonary Artery Hypertension Model
Published on: November 11, 2022
[Urapidil as a drug of choice for decreasing arterial pressure in surgical practice]
1Institute of Surgery named after A.V. Vishnevsky under the RF Ministry of Public Health, Moscow, Russia.
Abstract:
Arterial hypertension as a complication of the perioperative period is encountered in 6-20% of patients undergoing general surgical interventions. This article provides a detailed discussion of epidemiology and pathophysiological aspects of arterial hypertension in surgical patients, as well as physiology and the classification of the receptor complex participating in regulation of arterial pressure. Special attention is paid to clinical trials dedicated to using Urapidil (Ebrantil®) which belongs to the group of α1-adrenoblockers.
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