Stereotactic EEG via multiple single-path omnidirectional trajectories within a single platform: institutional...

Area of Science:

• Neurosurgery
• Epileptology
• Medical Device Technology

Background:

• Stereotactic electroencephalography (SEEG) is increasingly utilized for diagnosing complex epileptic foci.
• Existing SEEG methods can be cumbersome or costly.
• Refractory epilepsy necessitates precise localization of seizure origins.

Purpose of the Study:

• To describe a novel 3D-printed omnidirectional platform for SEEG.
• To evaluate the accuracy and clinical efficacy of this new SEEG technique.
• To assess factors influencing localization error in SEEG electrode placement.

Main Methods:

• A hypothesis-driven SEEG plan informed the 3D printing of a single-path, multiple-trajectory platform.
• Electrodes were sequentially inserted after platform fixation.
• Multivariate linear regression analyzed localization errors in 15 patients over 18 months.

Main Results:

• 137 electrodes were successfully implanted in 15 patients with focal epilepsy.
• Mean entry point localization error was 1.42 mm; mean target point error was 3.36 mm.
• Platform distance, trajectory angle, and intracranial distance impacted localization error.

Conclusions:

• The novel omnidirectional platform provides accurate SEEG localization with favorable clinical outcomes.
• This technique avoids the need for cumbersome frames and high costs.
• It represents a viable advancement in epilepsy monitoring technology.