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Chorioretinal Perfusion in Persistent Placoid Maculopathy
Abstract:
Persistent placoid maculopathy (PPM) is a rare clinical entity that has previously been reported in the literature with a characteristic appearance on multimodal imaging, including hypofluorescence observed on fluorescein angiogram (FA) and indocyanine green angiography (ICGA). The leading mechanisms proposed for this hypofluorescence include impaired choroidal vasculature with nonperfusion of the choriocapillaris and/or blockage of choroidal fluorescence by inflammatory deposits. This report demonstrates previously unreported characteristics of chorioretinal perfusion in a case of acute onset PPM in a 58-year-old woman. Optical coherence tomography angiography confirmed hypoperfusion of the choriocapillaris corresponding to the hypoperfusion seen on FA and ICGA. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:1026-1031.].
Insights
Persistent placoid maculopathy (PPM) is a rare eye condition. New imaging reveals reduced blood flow in the choriocapillaris as a key feature of acute PPM.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Choroidal Vasculature
Background:
- Persistent placoid maculopathy (PPM) is a rare condition characterized by specific multimodal imaging findings.
- Hypofluorescence on fluorescein angiography (FA) and indocyanine green angiography (ICGA) is typical, with proposed mechanisms including impaired choroidal vasculature or inflammatory deposits.
Observation:
- This case report details a 58-year-old woman with acute onset PPM.
- Novel imaging characteristics of chorioretinal perfusion were observed.
Findings:
- Optical coherence tomography angiography (OCTA) confirmed hypoperfusion of the choriocapillaris.
- This hypoperfusion correlated with the hypofluorescent areas seen on FA and ICGA.
Implications:
- These findings enhance understanding of the pathophysiology of acute PPM.
- OCTA provides valuable insights into chorioretinal perfusion abnormalities in PPM.
- This may aid in refining diagnostic and therapeutic strategies for PPM.
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