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Chorioretinal Perfusion in Persistent Placoid Maculopathy.

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    Persistent placoid maculopathy (PPM) is a rare eye condition. New imaging reveals reduced blood flow in the choriocapillaris as a key feature of acute PPM.

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    Area of Science:

    • Ophthalmology
    • Retinal Imaging
    • Choroidal Vasculature

    Background:

    • Persistent placoid maculopathy (PPM) is a rare condition characterized by specific multimodal imaging findings.
    • Hypofluorescence on fluorescein angiography (FA) and indocyanine green angiography (ICGA) is typical, with proposed mechanisms including impaired choroidal vasculature or inflammatory deposits.

    Observation:

    • This case report details a 58-year-old woman with acute onset PPM.
    • Novel imaging characteristics of chorioretinal perfusion were observed.

    Findings:

    • Optical coherence tomography angiography (OCTA) confirmed hypoperfusion of the choriocapillaris.
    • This hypoperfusion correlated with the hypofluorescent areas seen on FA and ICGA.

    Implications:

    • These findings enhance understanding of the pathophysiology of acute PPM.
    • OCTA provides valuable insights into chorioretinal perfusion abnormalities in PPM.
    • This may aid in refining diagnostic and therapeutic strategies for PPM.