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Retinal vasculitis associated with cutaneous leukocytoclastic vasculitis
1Retina and Uveitis Services, L V Prasad Eye Institute, Patia, Bhubaneswar, 751024, India. eyetalk@gmail.com.
International Ophthalmology
|December 20, 2017
Summary
This case study highlights the first instance of retinal vasculitis linked to cutaneous leukocytoclastic vasculitis. Early treatment with corticosteroids and methotrexate led to resolution of both skin and eye conditions.
Area of Science:
- Ophthalmology
- Dermatology
- Rheumatology
Background:
- Retinal vasculitis can present with vision-threatening complications such as vitreous hemorrhage.
- Cutaneous leukocytoclastic vasculitis is a common form of small vessel vasculitis.
Observation:
- A 28-year-old man presented with occlusive retinal vasculitis and vitreous hemorrhage.
- He also had a history of Enterobacter epididymo-orchitis and recurrent skin nodules.
- Skin biopsy confirmed leukocytoclastic vasculitis.
Findings:
- The patient experienced recurrent retinal vasculitis and skin lesions.
- Both ocular and cutaneous manifestations resolved with oral corticosteroids and methotrexate.
- No recurrence was observed over a six-year follow-up period.
Implications:
- This case suggests a potential association between retinal vasculitis and cutaneous leukocytoclastic vasculitis.
- Systemic immunosuppressive therapy may be effective in managing combined ocular and cutaneous vasculitis.
- Further research is warranted to explore this association and its underlying mechanisms.
