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Updated: Feb 16, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Pemphigus foliaceus with pustular presentation in a patient with psoriasis
Vando Barbosa de Sousa1, Cândida Naira Lima E Lima Santana1, Daniele do Nascimento Pereira1
1Dermatology Department at Hospital Universitário Pedro Ernesto, of the Universidade do Estado do Rio de Janeiro (Hupe-Uerj) - Rio de Janeiro (RJ), Brazil.
Abstract:
Pemphigus foliaceus is a chronic autoimmune disease of the skin, clinically characterized by scaly and crusty cutaneous erosions involving the seborrheic areas. The patient can eventually become erythrodermic. There are reports of atypical cases of pemphigus foliaceus with pustules and neutrophils, and clinical differentiation from generalized pustular psoriasis of von Zumbusch is difficult. We report the case of a 55-year-old man with a history of psoriasis vulgaris that has developed pemphigus foliaceus with pustules, triggered by withdrawal of systemic corticosteroids. This is the first report associating this atypical form of pemphigus with psoriasis, suggesting that an overlap with generalized pustular psoriasis can occur.
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