Related Experiment Video

Updated: Feb 16, 2026

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
10:22

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Published on: December 4, 2015

9.4K

Malaria in Children

Natasha M Kafai1, Audrey R Odom John2

  • 1Medical Scientist Training Program, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8226, St Louis, MO 63110, USA.

Infectious Disease Clinics of North America
|December 23, 2017
PubMed

Insights

Pediatric malaria is a global health concern, with imported cases rising due to international travel. This article reviews the epidemiology, clinical aspects, diagnosis, treatment, and prevention of malaria in traveling children.

Area of Science:

  • Global Health
  • Infectious Diseases
  • Pediatrics

Background:

  • Malaria is a significant global disease, posing risks to travelers worldwide.
  • Imported malaria cases, particularly in children, are increasing due to global travel.
  • Understanding pediatric malaria is crucial for effective public health interventions.

Purpose of the Study:

  • To provide a comprehensive overview of pediatric malaria in travelers.
  • To consolidate information on the epidemiology, clinical presentation, and management of pediatric malaria.
  • To highlight key aspects of diagnosis, treatment, and prevention strategies.

Main Methods:

  • Literature review of pediatric malaria epidemiology.
  • Analysis of clinical features and diagnostic approaches for pediatric malaria.
  • Synthesis of current treatment guidelines and prevention recommendations.

Main Results:

  • Pediatric malaria presents unique challenges in diagnosis and management.
  • Early recognition and prompt treatment are critical for favorable outcomes.
  • Effective prevention strategies are essential for protecting traveling children.

Conclusions:

  • Pediatric malaria requires tailored approaches considering age-specific factors.
  • Travelers' health education and chemoprophylaxis are vital for malaria prevention.
  • Continued surveillance and research are necessary to combat pediatric malaria globally.

Keywords:
Antiparasitic therapyChemoprophylaxisDiagnosticsFeverMalariaTravel medicine

More Related Videos

In Vitro Assay of Plasmodium-Infected Red Blood Cell Killing by Cytotoxic Lymphocytes08:20

In Vitro Assay of Plasmodium-Infected Red Blood Cell Killing by Cytotoxic Lymphocytes

Published on: August 17, 2022

2.7K
In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging09:04

In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging

Published on: June 8, 2017

6.9K

Related Concept Videos

Symbiosis00:58

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
37.7K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
284
Diversity of Protists II01:27

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
1.2K
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
256
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
323
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
335