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Management of Ebola Virus Disease in Children

Indi Trehan1, Stephanie C De Silva2

  • 1Lao Friends Hospital for Children, Luang Prabang, Lao PDR; Department of Pediatrics, One Children's Place, Campus Box 8116, St Louis, MO 63110, USA; Maforki Ebola Holding and Treatment Centre, Port Loko, Sierra Leone.

Infectious Disease Clinics of North America
|December 23, 2017
PubMed

Insights

Clinical management of pediatric Ebola cases improved during the 2013-2016 West Africa epidemic. Lessons learned emphasize early, aggressive critical care, including fluids, electrolytes, antimicrobials, and nutrition for future outbreaks.

Area of Science:

  • Infectious Diseases
  • Pediatric Critical Care
  • Epidemiology

Background:

  • The 2013-2016 West African Ebola epidemic was the largest recorded.
  • Tens of thousands of patients were treated, providing significant clinical experience.
  • Pediatric Ebola case management in austere settings requires specialized knowledge.

Purpose of the Study:

  • To summarize key aspects of pediatric Ebola case management.
  • To provide a firsthand account based on the West African outbreak.
  • To prepare for future Ebola epidemics.

Main Methods:

  • Review of clinical experiences during the 2013-2016 Ebola outbreak.
  • Focus on pediatric patients in resource-limited (austere) settings.
  • Emphasis on critical care interventions.

Main Results:

  • Optimized clinical care strategies for children with Ebola were identified.
  • Early and aggressive critical care is crucial.
  • Key interventions include fluid resuscitation, electrolyte repletion, antimicrobial therapy, and nutritional support.

Conclusions:

  • Lessons from the West African Ebola epidemic can optimize pediatric care.
  • Aggressive critical care is vital for improving outcomes in pediatric Ebola patients.
  • Preparedness for future outbreaks relies on summarizing and applying this knowledge.

Keywords:
ChildrenClinical managementCritical careDiagnosisEbolaPediatricsScreeningTherapy

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