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Updated: Feb 16, 2026

Optimization of the Cuff Technique for Murine Heart Transplantation
Published on: June 26, 2020
Honoring 50 Years of Clinical Heart Transplantation in Circulation: In-Depth State-of-the-Art Review
Josef Stehlik1, Jon Kobashigawa2, Sharon A Hunt3
1Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City (J.S.) josef.stehlik@hsc.utah.edu.
Abstract:
Heart transplantation has become a standard therapy option for advanced heart failure. The translation of heart transplantation from innovative experiments to long-term clinical success has married prescient insights with discipline and organization in the domains of surgical techniques, organ preservation, immunosuppression, organ donation and transplantation logistics, infection control, and long-term graft surveillance. This review explores the key milestones of the past 50 years of heart transplantation and discusses current challenges and promising innovations on the clinical horizon.
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