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Personalized Medicine in Preschool Children with Asthma

Hengameh Raissy1, Kathryn Blake2

  • 1Department of Pediatrics, School of Medicine, University of New Mexico, Albuquerque, New Mexico.

Pediatric Allergy, Immunology, and Pulmonology
|December 28, 2017
PubMed

Insights

Personalized medicine offers new hope for managing childhood asthma. This review highlights recent advances in tailoring treatments for preschool children with wheezing, improving their health outcomes.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology
  • Personalized Medicine

Background:

  • Asthma management in preschool children is complex due to varied early-life phenotype presentations.
  • Identifying specific phenotypes and biomarkers is crucial for optimizing asthma treatment strategies.
  • Current approaches require refinement to effectively manage wheezing in young children.

Purpose of the Study:

  • To review and summarize recent research on personalized medicine approaches for preschool children with wheezing.
  • To highlight the importance of phenotype and biomarker identification in guiding treatment decisions.
  • To provide an overview of current advancements in tailoring asthma management for this age group.

Main Methods:

  • Literature review of recent studies focusing on personalized medicine in pediatric asthma.
  • Analysis of data on preschooler wheezing phenotypes and relevant biomarkers.
  • Synthesis of findings related to treatment optimization strategies.

Main Results:

  • Recent data suggests personalized medicine can significantly improve asthma management in preschool children.
  • Phenotypic heterogeneity in early life impacts treatment response.
  • Biomarker discovery is advancing, offering potential for targeted therapies.

Conclusions:

  • Personalized medicine holds promise for optimizing asthma care in preschool children.
  • Further research into distinct wheezing phenotypes and biomarkers is essential.
  • Tailored treatment strategies are key to improving outcomes for young children with asthma.

Keywords:
asthmapersonalized medicinepreschool children

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