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Updated: Feb 16, 2026

Tobacco Hornworm as an Insect Model System for Cannabinoid Pre-clinical Studies
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Cannabinoids and Symptomatic Bradycardia
Mark R Heckle1, Mannu Nayyar1, Scott E Sinclair2
1Division of Cardiovascular Diseases.
Abstract:
Cannabinoids, the bioactive components of marijuana, have adverse cardiovascular consequences, including symptomatic sinus bradycardia, sinus arrest and ventricular asystole. Physicians should be aware of these deleterious consequences which can appear in otherwise healthy persons who are chronic marijuana users.
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