Related Experiment Videos

α-Synuclein and Tau: Mitochondrial Kill Switches.

Ulrike Pech1, Patrik Verstreken1

  • 1VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, 3000 Leuven, Belgium.

Neuron
|January 5, 2018
PubMed
Summary

Alpha-synuclein disrupts the actin network, leading to mitochondrial fission defects in Parkinson's disease. This finding suggests converging neurodegenerative pathways involving alpha-synuclein and the Parkinson's disease risk factor Tau.

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