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Updated: Feb 15, 2026

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
Published on: December 1, 2023
Preoperative optimization of ocular surface disease before cataract surgery
Jasmine Chuang1, Kendrick Co Shih1, Tommy C Chan1
1From the Li Ka Shing Faculty of Medicine (Chuang) and the Department of Ophthalmology (Shih), University of Hong Kong, the Department of Ophthalmology and Visual Sciences (Chan, Jhanji), Faculty of Medicine, the Chinese University of Hong Kong, Department of Ophthalmology (Wan), Tuen Mun Eye Centre and Tuen Mun Hospital, Hong Kong, China; the Department of Ophthalmology (Jhanjij), University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania USA; the Ocular Surface Research Group (Tong), Singapore Eye Research Institute, the Corneal and External Eye Disease Service (Tong), Singapore National Eye Centre, the Eye-Academic Clinical Program (Tong), Duke-NUS Medical School, and the Department of Ophthalmology (Tong), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Cataract surgery can worsen dry eye disease and ocular surface health, impacting surgical outcomes. Early recognition and aggressive management of dry eye are crucial for patients undergoing cataract surgery.
Area of Science:
- Ophthalmology
- Cornea and Ocular Surface Disease
Background:
- An impaired ocular surface complicates cataract surgery planning and execution.
- Dry eye disease (DED) is a common condition that can be exacerbated by ocular procedures.
Purpose of the Study:
- To review the relationship between cataract surgery and dry eye.
- To determine optimal management strategies for patients with dry eye undergoing cataract surgery.
Main Methods:
- A literature review was conducted.
- Included 16 papers, with 6 randomized controlled trials.
Main Results:
- Cataract surgery was found to worsen ocular parameters and aggravate DED.
- Factors like increased incision extent, operation time, and light exposure reduced tear breakup time and goblet cell density.
- Postoperative eyedrop use was linked to decreased goblet cell density.
Conclusions:
- Physicians must identify and aggressively treat cataract patients with pre-existing DED or poor prognostic factors.
- Management should include tapering off unnecessary postoperative eyedrops to improve ocular surface health.
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