Trends, Challenges, and Opportunities Regarding Research in Non-traumatic Spinal Cord Dysfunction

Area of Science:

• Neurology
• Rehabilitation Medicine
• Epidemiology

Background:

• Spinal cord dysfunction (SCDys) encompasses diverse conditions with rising incidence.
• Rehabilitation research for SCDys is growing but encounters significant obstacles.

Purpose of the Study:

• To review changes in SCDys research over four decades.
• To identify challenges in SCDys research.
• To propose opportunities for research enhancement.

Main Methods:

• Triangulation approach combining literature search (MEDLINE, Embase, 1974-2016) and expert workshop discussions.
• Analysis of publications and clinical rehabilitation research expertise.
• International Spinal Cord Society annual meeting workshop (2016).

Main Results:

• Substantial increase in SCDys publications (1,825 in 1974-1983 to 11,887 in 2004-2013) with improved methodology.
• Key research challenges identified: case identification, study design, data collection, funding, preclinical, and international collaboration.
• Opportunities for research improvement were identified.

Conclusions:

• Growing publication numbers underscore the significance of SCDys research.
• Lack of high-quality epidemiological studies (incidence, prevalence, survival) hinders evidence-based care and policy.
• Addressing research challenges is crucial for advancing SCDys patient management.