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Changes in Caries Risk in a Practice-Based Randomized Controlled Trial.

P Rechmann1, B W Chaffee1, B M T Rechmann1

  • 11 Department of Preventive and Restorative Dental Sciences, School of Dentistry, University of California at San Francisco, San Francisco, CA, USA.

Advances in Dental Research
|January 23, 2018
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Summary
This summary is machine-generated.

Caries Management by Risk Assessment (CAMBRA) significantly reduced high-caries-risk participants to lower risk levels in a 2-year dental practice trial. This preventive approach proved effective in managing dental caries risk.

Keywords:
Caries Management by Risk Assessment (CAMBRA)Practice-Based Research Network (PBRN)caries preventioncaries risk assessmentdental cariesdisease indicators

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Area of Science:

  • Dental Public Health
  • Preventive Dentistry
  • Clinical Trials

Background:

  • Dental caries remains a significant public health issue.
  • Effective implementation of preventive strategies in dental practice is crucial for caries control.
  • Caries Management by Risk Assessment (CAMBRA) offers a structured approach to personalized caries prevention.

Purpose of the Study:

  • To evaluate the successful implementation of Caries Management by Risk Assessment (CAMBRA) in a dental practice setting.
  • To assess the effectiveness of CAMBRA in reducing caries risk levels over a 2-year period.
  • To compare CAMBRA intervention with standard of care in managing participants' caries risk.

Main Methods:

  • A 2-year, randomized, controlled, parallel-arm, double-blind clinical trial involving 460 participants.
  • Dentists assigned participants to either standard of care or active CAMBRA treatment.
  • Caries risk assessment and management strategies were applied at baseline and regular recall visits.

Main Results:

  • Among initially high-risk participants, the CAMBRA intervention group showed a significantly lower percentage remaining at high risk (25%) compared to the control group (54%) at 24 months (P = 0.003).
  • Most participants initially assessed as low risk remained at low risk in both groups, with 89% in the intervention group and 71% in the control group at 24 months (P = 0.18).
  • The intervention group consistently showed a greater reduction in recorded disease indicators among initially high-risk participants.

Conclusions:

  • Caries Management by Risk Assessment (CAMBRA) can be successfully implemented in dental practice.
  • CAMBRA effectively reduces caries risk in participants initially assessed as high risk.
  • CAMBRA supports maintaining low caries risk status for participants initially assessed as low risk.