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Morbihan disease: a therapeutic challenge
Fernanda Cabral1, Lara Caroline Lubbe1, Monisa Martins Nóbrega1
1Dermatology Service at Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro (HUPE-UERJ) - Rio de Janeiro (RJ), Brazil.
Anais Brasileiros De Dermatologia
|January 25, 2018
Summary
Morbihan disease, a rare facial swelling linked to rosacea, often shows poor treatment response. A combination of deflazacort and isotretinoin proved effective, but gradual corticosteroid tapering is crucial to prevent recurrence.
Area of Science:
- Dermatology
- Ophthalmology
Background:
- Morbihan disease is a rare condition causing chronic facial edema, often linked to rosacea.
- It presents with variable therapeutic responses and significant refractoriness.
Observation:
- A 61-year-old male with a history of rosacea was diagnosed with Morbihan disease.
- The patient experienced significant improvement with a combination of deflazacort and oral isotretinoin.
Findings:
- Recurrence of facial lymphedema was observed after discontinuing corticosteroids.
- The combination therapy demonstrated excellent efficacy in managing severe facial lymphedema.
Implications:
- This combination therapy may be effective for severe facial lymphedema in Morbihan disease.
- Gradual corticosteroid discontinuation is recommended to prevent disease recurrence.
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