Pupillographic campimetry: an objective method to measure the visual field

Area of Science:

• Ophthalmology
• Neuroscience
• Medical Technology

Background:

• Pupillographic campimetry objectively measures visual fields via pupil response.
• Traditional methods like static perimetry require reliable subject fixation, a common limitation.
• Fixation instability can compromise the accuracy of visual field assessments.

Purpose of the Study:

• To introduce and validate gaze-controlled campimetry for retinotopic visual field examination.
• To overcome fixation problems inherent in conventional pupillographic methods.
• To assess the utility of gaze-controlled campimetry in detecting and classifying visual field defects.

Main Methods:

• Utilized stimulus sizes comparable to static perimetry.
• Integrated gaze tracking technology with pupillography.
• Applied the method to eight normal-sighted subjects and three patients with visual field-affecting diseases.

Main Results:

• Demonstrated reduced pupil response amplitude with increasing eccentricity in normal subjects.
• Successfully detected organic visual field defects in patients objectively.
• Classified visual field defects without an organic background.
• Evaluated visual field sensitivity loss beyond classical perimetry in retinitis pigmentosa patients.

Conclusions:

• Gaze-controlled pupil campimetry provides objective visual field assessment independent of fixation.
• The method enhances stability and spatial resolution compared to traditional techniques.
• It serves as a valuable tool for monitoring disease progression and as a biomarker for new treatments.