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Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs)

Ricarda M Hoffmann1,2, Ben G T Coumbe1,3, Debra H Josephs1,4

  • 1St. John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, Tower Wing, Guy's Hospital, London, United Kingdom.

Oncoimmunology
|January 30, 2018
PubMed

Keywords:
AntibodiesAntibody Drug Conjugate (ADC)IgG1IgG4Immunoglobulin Fcbiodistributioneffector functionskineticsstability

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