Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ideal Solutions02:24

Ideal Solutions

22.7K
According to Raoult’s law, the partial vapor pressure of a solvent in a solution is equal or identical to the vapor pressure of the pure solvent multiplied by its mole fraction in the solution. However, Raoult's Law is only valid for ideal solutions. For a solution to be ideal, the solvent-solute interaction must be just as strong as a solvent-solvent or solute-solute interaction. This suggests that both the solute and the solvent would use the same amount of energy to escape to the...
22.7K
General Properties of Solutions02:12

General Properties of Solutions

36.2K
Many common substances around us exist as a solution, such as ocean water, air, and gasoline. All solutions are mixtures of substances that are composed of varying amounts of two or more types of atoms or molecules. A mixture with a non-uniform composition is a heterogeneous mixture, whereas a mixture with a uniform composition is a homogeneous mixture. The components that make the homogeneous mixture are evenly spread out and thoroughly mixed. 
36.2K
Solution Formation02:16

Solution Formation

38.2K
There is no one solvent that can dissolve every type of solute. Some substances that readily dissolve in a certain solvent might be insoluble in a different solvent. A simple way to predict which substances dissolve in which solvent is the phrase "like dissolves like". This means that polar substances, such as salt and sugar, dissolve in a polar substance like water. In contrast, non-polar substances are more soluble in non-polar solvents such as carbon tetrachloride.
This selective...
38.2K
Enthalpy of Solution02:39

Enthalpy of Solution

31.3K
There are two criteria that favor, but do not guarantee, the spontaneous formation of a solution:
31.3K
Standard Solutions01:14

Standard Solutions

2.6K
Standard solutions refer to solutions with a precisely known concentration or composition. A primary standard is a highly pure, high molar mass, stable substance that is entirely soluble in water, the most commonly used solvent in analytical chemistry. The primary standard solution can be used to standardize secondary standards, which are substances with known concentrations but are less pure and stable. Standard solutions are essential for achieving accurate and reliable results in analytical...
2.6K
Blank Solutions00:56

Blank Solutions

1.3K
A blank solution is a solution that does not contain the analyte, or the substance of interest being tested or measured. It is typically prepared using the same reagents and procedure as the sample solution but without adding the analyte. The primary purpose of preparing a blank solution is to account for any background interference or contamination that may affect the accuracy and reliability of the analytical method.
In some experimental cases, the reagents, solvents, or lab equipment used in...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical and biological factors associated with the presence of peripheral neuropathy in patients with rheumatoid arthritis.

Frontiers in neurology·2026
Same author

Oral health knowledge and practices of people living with type 2 diabetes in three health facilities in the Dschang Health District, West Region, Cameroon.

The Pan African medical journal·2026
Same author

Prevalence and factors associated with chronic low back pain in students of the university of Dschang: a cross-sectional study in a sub-Saharan university.

Frontiers in pain research (Lausanne, Switzerland)·2026
Same author

EUROVISCO Recommendations for the Use of Viscosupplementation with Hyaluronic Acid in the Management of Hip Osteoarthritis.

Cartilage·2026
Same author

Factors associated with unacceptable knowledge, attitudes and practices of patients with type 2 diabetes on cardiovascular risk factors and diabetes-related complications in two health facilities of the West Region of Cameroon during the COVID-19 pandemic: a cross-sectional study.

BMJ open·2025
Same author

Prevalence and determinants of burnout among staff of the university of Dschang: a cross-sectional study in a Sub-Saharan university.

BMC public health·2025
Same journal

Autoantibody Ordering Patterns Across a Tertiary Hospital: A Retrospective Audit.

Open access rheumatology : research and reviews·2026
Same journal

Real-World Effectiveness of Biologic and Targeted Synthetic Therapies in Rheumatoid Arthritis: a Multicenter Study from Rheumatoid Arthritis Saudi Database (RASD).

Open access rheumatology : research and reviews·2026
Same journal

Lupus Enteritis Presenting as Acute Abdomen with Clear Gelatinous Stools in a Woman with Systemic Lupus Erythematosus: A Case Report and Literature Review.

Open access rheumatology : research and reviews·2026
Same journal

Guillain-Barré Syndrome, Subtype AMAN, Can Only Be Attributed to Lupus Erythematosus if All Infectious Causes Have Been Ruled Out [Response to Letter].

Open access rheumatology : research and reviews·2026
Same journal

Guillain-Barré Syndrome, Subtype AMAN, Can Only Be Attributed to Lupus Erythematosus if All Infectious Causes Have Been Ruled Out [Letter].

Open access rheumatology : research and reviews·2026
Same journal

Vascular Involvement in Behçet's Disease: A Retrospective Analysis of Qatar Behçet's Cohort.

Open access rheumatology : research and reviews·2026
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
08:31

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

714

Refractory relapsing polychondritis: challenges and solutions.

Fernando Kemta Lekpa1,2, Xavier Chevalier3

  • 1Faculty of Health Sciences, University of Buea, Buea.

Open Access Rheumatology : Research and Reviews
|February 3, 2018
PubMed
Summary
This summary is machine-generated.

Relapsing polychondritis is a rare immune disease causing cartilage destruction. More research and data sharing are needed for better diagnosis, prognosis, and evidence-based treatment guidelines.

Keywords:
biologicscriteriadiagnosisdisease activityrelapsing polychondritistreatments

More Related Videos

Glioblastoma Relapse Post-Resection Model for Therapeutic Hydrogel Investigations
04:46

Glioblastoma Relapse Post-Resection Model for Therapeutic Hydrogel Investigations

Published on: February 24, 2023

2.3K
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

11.1K

Related Experiment Videos

Last Updated: Feb 15, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
08:31

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia

Published on: October 17, 2025

714
Glioblastoma Relapse Post-Resection Model for Therapeutic Hydrogel Investigations
04:46

Glioblastoma Relapse Post-Resection Model for Therapeutic Hydrogel Investigations

Published on: February 24, 2023

2.3K
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

11.1K

Area of Science:

  • Rheumatology
  • Immunology
  • Genetics

Background:

  • Relapsing polychondritis (RP) is a rare, severe systemic immune-mediated disease.
  • It is characterized by episodic inflammation and progressive destruction of cartilaginous structures.
  • Despite its long history, RP remains poorly understood, with unknown incidence and prevalence.

Purpose of the Study:

  • To highlight the diagnostic and therapeutic challenges in managing relapsing polychondritis.
  • To emphasize the need for improved understanding of RP pathophysiology.
  • To advocate for collaborative efforts in data sharing for advancing RP research.

Main Methods:

  • This study is a review of the current understanding and challenges in relapsing polychondritis.
  • It synthesizes existing knowledge on pathophysiology, diagnosis, and treatment.
  • It proposes solutions based on international data sharing and collaborative research.

Main Results:

  • Relapsing polychondritis presents with diverse clinical manifestations, leading to diagnostic delays.
  • Current management lacks validated guidelines, and treatment is often empirical.
  • Understanding RP pathophysiology, developing new diagnostic criteria (including biomarkers and imaging), and predicting severe outcomes remain significant challenges.

Conclusions:

  • International data sharing from reference centers is crucial for advancing relapsing polychondritis knowledge.
  • This collaboration can lead to improved diagnostic criteria, prognostic tools, and evidence-based therapeutic guidelines.
  • Future research should focus on randomized controlled trials to establish effective treatments for relapsing polychondritis.