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Updated: Feb 15, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Organizing a clinical trial for the new investigator
Janet Baack Kukreja1, Ian M Thompson2, Brian F Chapin1
1Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Background And Purpose:
Clinical trials organization can be daunting especially when orienting to a new system. The steps to a successful clinical trial are not concrete and vary based on the system.
Methods:
In this section the discussion centers on how to shape the question for the clinical trial which is rational and feasible to answer within the planned study design.
Findings:
Senior mentorship, collaboration and early involvement of stakeholders can help shape a successful clinical trial. Keeping in mind ethics and the processes within a system will make planning easier. Questions about key elements of the trial should be answered early to prevent delays of study initiation.
Conclusion:
Clinical trial development and implementation can be very rewarding, but successful outcomes require careful planning and considerations.
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