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Updated: Jan 10, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Current and Upcoming Trials in Localized Prostate Cancer
Landan P MacDonald1, Andrew M Fang1, Chad Tang2
1Department of Urology, Unit 1373, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
None:
The diagnosis and management of localized prostate cancer (PCa) remains an active field of research, with many recently published and upcoming clinical trials. Advances in local therapy, management of pelvic lymph nodes, imaging, systemic treatments, and quality of life have the potential to optimize outcomes while minimizing toxicity. This review synthesizes findings from recently completed phase III trials, highlights ongoing studies and provides an update on evidence-based management approaches and emerging innovations which may improve the care of patients with localized PCa.
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