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Related Experiment Videos

Risperidone Related Raynaud's Phenomenon: An Adolescent Case.

Serkan Güneş1, Özalp Ekinci2, Halenur Teke2

  • 1Department of Child and Adolescent Psychiatry, Hatay State Hospital, Hatay, Turkey.

Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology
|February 6, 2018
PubMed
Summary

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Risperidone, an antipsychotic, may trigger Raynaud

Area of Science:

  • Pharmacology
  • Pediatric Psychiatry
  • Vascular Medicine

Background:

  • Raynaud's phenomenon is a vasospastic disorder causing reduced peripheral blood flow, triggered by cold or stress.
  • Certain medications, including psychostimulants and aripiprazole, have been linked to Raynaud's phenomenon.
  • Risperidone, an atypical antipsychotic, affects dopaminergic and serotonergic systems and is used in pediatric patients.

Observation:

  • A 12-year-old boy developed Raynaud's phenomenon.
  • The condition emerged two weeks after initiating risperidone treatment.
  • Symptoms resolved upon discontinuation of risperidone.

Findings:

  • This case report details an association between risperidone use and the onset of Raynaud's phenomenon in an adolescent.
Keywords:
AdolescentCase reportChildRaynaud's phenomenonRisperidone

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  • The temporal relationship suggests a potential drug-induced etiology.

    • Implications:

    • Clinicians should consider risperidone as a potential cause of Raynaud's phenomenon in pediatric patients.
    • Further research may be warranted to explore the mechanism of this adverse drug reaction.
    • This finding highlights the importance of monitoring for peripheral vascular side effects during risperidone therapy.