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Enema of Traditional Chinese Medicine for Patients with Severe Acute Pancreatitis
Published on: January 27, 2023
Penta-therapy for severe acute hyperlipidemic pancreatitis
1Department of ICU, Shanghai General Hospital, Shanghai Jiao Tong University School of medicine, No. 650 New Songjiang Road, Songjiang, Shanghai 201600, China.
Penta-therapy, a novel treatment for severe acute pancreatitis (SAP), significantly improved patient outcomes and reduced key biomarkers compared to conventional therapy alone. This approach offers a promising alternative for managing SAP.
Area of Science:
- Gastroenterology
- Internal Medicine
- Critical Care Medicine
Background:
- Severe acute pancreatitis (SAP) presents significant clinical challenges.
- Optimizing treatment protocols for SAP is crucial for improving patient outcomes and reducing mortality.
Purpose of the Study:
- To evaluate the efficacy of a novel penta-therapy regimen in treating severe acute pancreatitis (SAP).
- To compare the clinical outcomes and biomarker profiles of patients receiving penta-therapy versus conventional treatment.
Main Methods:
- A retrospective study was conducted on 88 patients with severe acute pancreatitis (SAP) between 2007 and 2016.
- Patients were divided into a control group (conventional treatment) and a penta-therapy group (conventional treatment plus blood purification, antihyperlipidemic agents, low-molecular-weight heparin, insulin, and traditional Chinese medicine).
- Key clinical outcomes and serum biomarkers were assessed and compared between the two groups.
Main Results:
- Penta-therapy significantly reduced serum amylase, triglyceride, white blood cell count, C-reactive protein, and blood sugar levels.
- Serum calcium levels were significantly increased in the penta-therapy group.
- Patients receiving penta-therapy experienced a significantly shorter hospital length of stay compared to the control group.
Conclusions:
- The addition of penta-therapy to conventional treatment for severe acute pancreatitis (SAP) demonstrates superior efficacy.
- Penta-therapy shows potential for improving both serum biomarkers and clinical outcomes in SAP patients.
- This regimen offers a promising therapeutic strategy for managing severe acute pancreatitis.
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