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Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting
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His Bundle Pacing: Is It Ready for Prime Time?

Fatima M Ezzeddine1, Gopi Dandamudi1

  • 1Indiana University School of Medicine, 1801 North Senate Boulevard, Suite 4000, Indianapolis, IN 46032, USA.

Cardiac Electrophysiology Clinics
|February 12, 2018
PubMed
Summary
This summary is machine-generated.

Permanent His bundle pacing offers a physiologic alternative to traditional pacing, potentially reducing risks like heart failure and atrial fibrillation associated with long-term right ventricular pacing.

Keywords:
Bundle branch blockHis bundle pacingPacing strategiesVentricular pacing

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Long-term right ventricular apical pacing is linked to adverse outcomes such as heart failure and atrial fibrillation.
  • These risks stem from ventricular dyssynchrony caused by altered ventricular depolarization.

Observation:

  • Biventricular pacing shows limited efficacy in patients without left bundle branch block and with reduced ejection fraction.
  • There is a need for pacing methods that restore natural cardiac conduction.

Findings:

  • Permanent His bundle pacing represents a physiologic approach to ventricular pacing.
  • This technique has demonstrated safety and feasibility in clinical settings.

Implications:

  • His bundle pacing may mitigate the adverse effects of conventional pacing by promoting synchronous ventricular activation.
  • It offers a promising alternative for patients requiring cardiac pacing, potentially improving long-term outcomes.