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Dietary Supplements with Antiplatelet Activity: A Solution for Everyone?
1Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Advances in Nutrition (Bethesda, Md.)
|February 14, 2018
Summary
Dietary supplements show potential for cardiovascular health by affecting blood platelets and coagulation. However, more human studies are needed to confirm their safety and efficacy, especially alongside traditional therapies.
Area of Science:
- Cardiovascular Medicine
- Nutritional Science
- Hematology
Background:
- Growing interest in nonpharmacologic, nutraceutical-based treatments for cardiovascular diseases.
- Dietary supplements are increasingly explored for their potential health benefits.
- Cardiovascular diseases remain a leading global health concern.
Purpose of the Study:
- To review the role of dietary supplements with antiplatelet activity in preventing and treating cardiovascular disorders.
- To examine the effects of these supplements on blood coagulation.
- To assess the current evidence regarding their safety and efficacy.
Main Methods:
- Literature review focusing on in vitro studies of dietary supplements.
- Analysis of effects on platelet aggregation and blood coagulation.
- Examination of interactions with conventional antiplatelet therapy.
Main Results:
- In vitro data suggest some dietary supplements possess antiplatelet and anticoagulant properties.
- Limited controlled human clinical trials exist to confirm these effects.
- Evidence for universal safety and benefit in all patients is lacking.
Conclusions:
- Dietary supplements may influence hemostasis, impacting cardiovascular risk factors.
- Further rigorous human clinical trials are essential to validate efficacy and safety.
- Monitoring platelet count, function, and coagulation parameters is advised for patients using these supplements, particularly around surgical procedures.
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