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Related Concept Videos

Aging01:26

Aging

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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The Effect of Aging on Tissues01:19

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Changes in the Appendicular Skeleton with Age01:09

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The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast
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Age Differences in Age Perceptions and Developmental Transitions.

William J Chopik1, Ryan H Bremner2, David J Johnson1

  • 1Department of Psychology, Michigan State University, East Lansing, MI, United States.

Frontiers in Psychology
|February 17, 2018
PubMed
Summary
This summary is machine-generated.

Older adults perceive aging later but feel younger than their age. Life expectancy desires increase after 40, shifting developmental transition ages later in life.

Keywords:
age differencesage perceptionsdevelopmental transitionsmiddle ageolder adulthoodproject implicit

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Area of Science:

  • Psychology
  • Gerontology
  • Sociology

Background:

  • Societal perceptions of aging influence individual self-perception.
  • Understanding age-related shifts in developmental timing is crucial for gerontological research.

Purpose of the Study:

  • To examine age differences in perceptions of aging and developmental transition timing.
  • To investigate how individuals estimate their own age and the onset of older adulthood.

Main Methods:

  • Analysis of a large-scale internet survey (N=502,548) with participants aged 10-89.
  • Examination of self-perceived age, desired age, and age estimates for life transitions.

Main Results:

  • Older adults reported older age perceptions but felt younger than their chronological age.
  • The desired lifespan significantly increased for individuals over 40.
  • Perceived ages for developmental transitions, particularly middle and older adulthood, were pushed later in life.

Conclusions:

  • Aging perceptions are complex, with individuals often feeling younger than their age.
  • The study highlights a significant shift in perceived life course timing with increasing age.
  • Findings offer novel insights into self-perception and aging across the lifespan.