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Vogt-Koyanagi-Harada syndrome Case report
Cristina Nicula1,1, Izabela Szabo1
1Ophthalmology Clinic, County Emergency Hospital Cluj-Napoca, Romania.
Romanian Journal of Ophthalmology
|February 17, 2018
Summary
Vogt-Koyanagi-Harada syndrome (VKH) rarely co-occurs with primary open-angle glaucoma (POAG). This case highlights challenges in managing VKH in diabetic patients requiring corticosteroids.
Area of Science:
- Ophthalmology
- Immunology
Background:
- Vogt-Koyanagi-Harada (VKH) syndrome is a rare multisystem inflammatory disease causing panuveitis and serous retinal detachment.
- Neurologic and cutaneous symptoms like headache, hearing loss, vitiligo, and poliosis often accompany VKH.
Observation:
- A 62-year-old female with diabetes mellitus and primary open-angle glaucoma (POAG) presented with decreased visual acuity.
- Ocular examination revealed bilateral keratic precipitates, posterior iris synechiae, and inferior retinal detachment.
- The patient had undergone prior glaucoma surgery and was on topical antiglaucoma medication.
Findings:
- The case presented a unique combination of VKH syndrome and POAG.
- Corticosteroid treatment, essential for VKH, was limited due to the patient's diabetes mellitus.
Implications:
- This case underscores the complexity of managing VKH syndrome in patients with pre-existing conditions like POAG and diabetes.
- The interaction between VKH, POAG, and diabetes necessitates careful treatment strategies, particularly regarding corticosteroid use.
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