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The Short Cosyntropin Test Revisited: New Normal Reference Range Using LC-MS/MS.

Grethe Å Ueland1,2,3, Paal Methlie1,2,3, Marianne Øksnes1,2,3

  • 1Department of Clinical Science, University of Bergen, Bergen, Norway.

The Journal of Clinical Endocrinology and Metabolism
|February 17, 2018
PubMed
Summary

New liquid chromatography tandem mass spectrometry (LC-MS/MS) cutoffs for the cosyntropin test improve diagnosis of adrenal insufficiency (AI) and nonclassical congenital adrenal hyperplasia (NCCAH). These precise LC-MS/MS ranges reduce false positives and negatives in steroid testing.

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