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Updated: Feb 14, 2026
08:58
Murine Kidney Transplant Technique
Published on: October 20, 2015
17.4K
Intestinal re-transplantation: indications, techniques and outcomes
Armando Ganoza1, Neslihan Celik, George V Mazariegos
1Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, USA.
Current Opinion in Organ Transplantation
|February 22, 2018
Summary
Intestinal retransplantation outcomes have significantly improved, offering a viable option for patients with irreversible intestinal failure. Advances in immunosuppression and surgical techniques enhance patient and graft survival, making this procedure more necessary.
Area of Science:
- Gastroenterology
- Transplantation Surgery
- Immunology
Background:
- Intestinal transplantation is the gold standard for irreversible intestinal failure.
- Early intestinal retransplantation faced high morbidity and mortality.
- Recent advancements have improved outcomes in intestinal retransplantation.
Purpose of the Study:
- To review recent progress in intestinal retransplantation outcomes.
- To highlight improvements in patient and graft survival.
- To summarize key factors contributing to better results.
Main Methods:
- Review of recent literature from high-volume transplant centers.
- Analysis of indications, surgical techniques, and complications.
- Evaluation of immunosuppression protocols and graft selection.
Main Results:
- Significant improvements in patient and graft survival reported.
- Common indications and surgical approaches identified.
- Advances in immunosuppression and liver-containing grafts noted.
Conclusions:
- Intestinal retransplantation is increasingly necessary due to improved survival.
- Current evidence supports its benefit in selected recipients.
- Optimized protocols for immunosuppression, surgery, and monitoring enhance outcomes.
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