Related Experiment Video
Updated: Feb 14, 2026
10:33
Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
21.9K
Development of microspheres for biomedical applications: a review
Kazi M Zakir Hossain1, Uresha Patel2, Ifty Ahmed3
1Bioengineering and Advanced Materials Research Group, University of Nottingham, University Park, Nottingham, NG7 2RD, UK. Zakir.Hossain@nottingham.ac.uk.
Progress in Biomaterials
|February 23, 2018
Summary
This review covers biomedical microspheres, including glass, ceramic, and polymer types. It details their applications in drug delivery and tissue engineering, alongside manufacturing challenges.
Area of Science:
- Biomaterials Science
- Materials Engineering
Background:
- Microspheres are increasingly vital in biomedical applications.
- Diverse materials like glasses, ceramics, and polymers are utilized.
- Various structures (porous, non-porous, hollow) are engineered for specific functions.
Purpose of the Study:
- To review recent literature on microsphere manufacturing for biomedical use.
- To discuss different microsphere types, structures, and their applications.
- To highlight preparation, characterization, and challenges.
Main Methods:
- Literature review of scientific publications.
- Analysis of microsphere materials (silicate, borate, phosphate glasses, ceramics, polymers).
- Examination of structural variations (porous, non-porous, hollow).
Main Results:
- Microspheres offer significant advantages in drug delivery, bone tissue engineering, and absorption/desorption processes.
- Various preparation and characterization techniques are employed for microsphere production.
- Key applications include controlled drug release and regenerative medicine.
Conclusions:
- Biomedical microspheres, derived from diverse materials, show great promise for advanced therapies.
- Further research is needed to overcome processing challenges and optimize microsphere performance.
- Continued development is essential for realizing the full potential of microspheres in medicine.
Related Concept Videos
01:10Review and Preview
8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
Percentiles are a type of fractile that partition data into...
8.4K
01:13Review and Preview
11.6K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.6K
01:43Sustainable Development
15.2K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.2K
01:22Language Development
939
Children master language quickly and with relative ease, supported by both biological predisposition and reinforcement. B. F. Skinner (1957) proposed that language is learned through reinforcement, while Noam Chomsky (1965) argued that language acquisition mechanisms are biologically determined.
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
939
01:15Development of the Lymphatic System
2.2K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
2.2K
01:28Applications of Logarithms
292
Logarithmic functions are powerful tools for simplifying the mathematical representation of phenomena involving exponential changes. Their ability to convert multiplicative relationships into additive ones is especially valuable in various scientific and engineering contexts. One notable application of logarithms is measuring sound intensity, specifically through the decibel (dB) scale used in acoustics.Sound intensity levels vary over an extensive range, from the faintest audible whisper to...
292